High-Fiber Additions : Incorporate dietary fibers like fruits, vegetables, and whole grains to improve digestive health and enhance the feeling of fullness
Exendin-4 significantly increased insulin level and phosphorylation of insulin receptor substrate 1 (IRS-1) in rat hippocampus, and could not change the status of tau phosphorylation without insulin in HT22 neurons, suggesting that insulin is required in reduction of tau hyperphosphorylation by GLP-1R agonists (154)
Sudden confusion, severe headache, difficulty speaking, weakness, vision changes, or altered consciousness may indicate serious conditions such as stroke, severe hypoglycemia, or other neurological emergencies
[5] Any insulin dose adjustments should only be made under clinical supervision
Diabetes 63 , 32213229 (2014)