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The fact that there's no active drug, it's not coming from the manufacturer, it's not covered by Health Canada, there's no regulation behind it anything could potentially happen, he said

Long-term weight maintenance after semaglutide requires either resuming treatment or adopting sustained lifestyle modifications that were difficult to maintain before

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If you suspect abnormal cortisol production, consult your GP for proper investigation, which may include referral to endocrinology services

The pivotal evidence for tirzepatide comes from the SURMOUNT program for weight management ( The New England Journal of Medicine , 2022) and SURMOUNT-OSA for obstructive sleep apnea (NEJM 2024), while the semaglutide STEP trials (NEJM 2021) anchor the single-agonist side