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No RCT was performed in patients with CTS, but results obtained from a recent multicenter, examiner-blinded, clinical and neurophysiological study are promising

Structural analysis together with mutagenesis data revealed mechanisms underlying agonism of different types of GHSR agonists and GHSR-G i coupling

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The field must avoid the pitfall of premature, broad clinical trials based solely on animal efficacy, which have historically led to disappointing results in neurology

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