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A2A receptor activation upregulates vascular endothelial growth factor (VEGF), promotes angiogenesis in the dermal microvasculature, stimulates fibroblast migration and proliferation, and suppresses inflammatory cytokine release

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This effect is characterized by elevation of glucose secretory response by oral glucose administration in comparison to intravenous administration even though they have similar plasma concentrations

Pevec, D., et al., Impact of pentadecapeptide BPC 157 on muscle healing impaired by systemic corticosteroid application