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Elevated ROS levels can lead to mitochondrial DNA damage, enzyme inhibition, and cellular dysfunction, ultimately contributing to disease progression (Sharifi-Rad et al., 2020)
T.LurbeE.ManciaG.et al (2020)
doi: 10.1111/j.1553-2712.2011.01041.x [DOI] [PubMed] [Google Scholar] 93.Schmidt LE, Knudsen TT, Dalhoff K, et al
Enhancements in neuronal homeostasis resulting from microglial depletion included the mitigation of post-TBI dendritic complexity, inhibition of most post-TBI transcriptional changes, interruption of neuronal connectivity and plasticity alongside functional deficits, and the mitigation of post-TBI cognitive impairments