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Studies published in Diabetes Care have examined patients with type 2 diabetes treated with liraglutide, demonstrating reductions in visceral adipose tissue measured by CT scan compared to placebo

For the efficacy estimand, the LSM change in HbA1c from baseline at week 52 as the primary endpoint was 2.24%, 2.43%, and 2.58% with tirzepatide 5, 10, and 15 mg, respectively, versus 1.44% with insulin glargine

Discussion In this systematic review and meta-analysis we summarised and synthesised the most up-to-date data from RCTs of once-weekly tirzepatide in individuals with type 2 diabetes

Subcutaneous absorption varies by site