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Aside from dimercaprol, sodium-calcium EDTA, DMPS, DMSA and its analogues, there are other chelators that are used in clinical therapy, namely deferoxamine (DFO) and D-Penicillamine

After receptor binding, intracellular pathways, including PI3K/Akt/mTOR and MEK/ERK, are activated, contributing to protein synthesis and anabolic signaling

Abstract This review provides an in-depth evaluation of two bioactive peptidesBPC-157 and TB-500which have attracted increasing interest in regenerative medicine for their potential therapeutic applications

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Yang et al., 2021