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As there is no meaningful expression of GLP-1 receptors on hepatocytes, the major effect of GLP-1 agonists on MASH is likely to be indirect and may be related to a reduction in calorie intake, body weight and insulin resistance, all of which would lead to reduced liver lipid accumulation and hepatic inflammation 7,8

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Med Sci Sports Exerc 14:377381 Bergstrom J (1975) Percutaneous needle biopsy of skeletal muscle in physiological and clinical research