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One commenter expressed concern that hospitals could avoid submitting Safety of Care measures to maintain a higher Overall Hospital Quality Star Rating and recommended awarding a 4- or 5-star rating only to hospitals that submit at least three measures from the Safety of Care group

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What we know : BPC-157 shows remarkable effects in animal models Three small human studies report positive results and no adverse events Short-term tolerance appears acceptable based on limited data What we dont know : Long-term safety in humans Optimal dosing for various conditions Drug interactions Efficacy for most claimed uses in humans Whether animal benefits translate to people The regulatory reality : FDA has restricted compounding due to safety concerns WADA prohibits use by athletes No country has approved BPC-157 for therapeutic use If you choose to use BPC-157, do so with clear eyes about the evidence gaps

Additionally, the afucosylated protein showed dose-dependent antitumor efficacy in severe combined immunodeficient (SCID) mouse and small effect in new generation of severely immunodeficient (NOG) mouse (169)